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is it necessary for 2 iscsi subnets

Team,

we have never used MPIO for our ESXI ISCSI conenctions and we are going to set up petasan as a primary target for our VEEAM backup data used by 1 ESXI host,

based on the hardware we have including switches and storage nodes is it a requirement to have 2 ISCSI subnets? Is it a reqiurement to use MPIO? and is it really necessary to have these subnets be 10g?

We are using HDD with SSD journals so from what I am seeing in forums and with a quick test on S3 storage we are not going to see performance from the storage system that would take advantage of 10G connections. S3 storage over 1g link was very slow and based on  the fact that we cant use S3 as a primary repository for Veeam (only a capacity tier) we would preferto just have ISCSI storage with the ability to scale

thanks for the input